{
 "name": "testosterone",
 "type": "concept",
 "episodes": [
  "the-diary-of-a-ceo-2026-06-22-dr-rachel-rubin-women-s-sexual-health-menopause-hormone-repl",
  "huberman-lab-2026-06-25-essentials-the-science-of-eating-for-health-fat-loss-lean-mu",
  "the-diary-of-a-ceo-2026-06-26-most-replayed-moment-sleep-expert-on-the-truth-about-melaton",
  "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g"
 ],
 "claims": [
  {
   "holder": "Rachel Rubin",
   "claim": "Testosterone is not a 'male hormone' — it is simply a hormone that women make too.",
   "stance": "assertion",
   "conviction": 0.9,
   "subjects": [
    "testosterone"
   ],
   "timestamp": "13:24",
   "quote": "Testosterone is just a hormone. It's not a male hormone, a female, it's just a hormone.",
   "episode_id": "the-diary-of-a-ceo-2026-06-22-dr-rachel-rubin-women-s-sexual-health-menopause-hormone-repl",
   "published_at": "2026-06-22"
  },
  {
   "holder": "Rachel Rubin",
   "claim": "Women's testosterone starts dropping precipitously in their 30s, but clinicians are not paying attention to it.",
   "stance": "assertion",
   "conviction": 0.85,
   "subjects": [
    "testosterone"
   ],
   "timestamp": "13:24",
   "quote": "This happens in your 30s and no one's paying attention.",
   "episode_id": "the-diary-of-a-ceo-2026-06-22-dr-rachel-rubin-women-s-sexual-health-menopause-hormone-repl",
   "published_at": "2026-06-22"
  },
  {
   "holder": "consensus",
   "reported_by": "Rachel Rubin",
   "claim": "There is global consensus that testosterone helps libido in post-menopausal women.",
   "stance": "fact_cited",
   "conviction": 0.9,
   "subjects": [
    "testosterone",
    "libido",
    "menopause"
   ],
   "timestamp": "19:47",
   "quote": "we have global consensus, actually, that testosterone helps for libido in post-menopausal women",
   "episode_id": "the-diary-of-a-ceo-2026-06-22-dr-rachel-rubin-women-s-sexual-health-menopause-hormone-repl",
   "published_at": "2026-06-22"
  },
  {
   "holder": "Rachel Rubin",
   "claim": "Birth control lowers testosterone, which can cause low libido and pain with sex in a subset of women.",
   "stance": "assertion",
   "conviction": 0.8,
   "subjects": [
    "birth control",
    "testosterone",
    "libido"
   ],
   "timestamp": "13:24",
   "quote": "one of the side effects is it lowers testosterone. And so that can cause low libido, pain with sex in a small subset of people who take it.",
   "episode_id": "the-diary-of-a-ceo-2026-06-22-dr-rachel-rubin-women-s-sexual-health-menopause-hormone-repl",
   "published_at": "2026-06-22"
  },
  {
   "holder": "Layne Norton",
   "claim": "At normal intakes of once or twice a day, soy does not appear to affect testosterone or estrogen.",
   "stance": "fact_cited",
   "conviction": 0.65,
   "subjects": [
    "soy",
    "testosterone"
   ],
   "timestamp": "16:05",
   "quote": "if you're just using it like once or twice a day, it doesn't seem to have an effect on testosterone or estrogen",
   "episode_id": "huberman-lab-2026-06-25-essentials-the-science-of-eating-for-health-fat-loss-lean-mu",
   "published_at": "2026-06-25"
  },
  {
   "holder": "Matthew Walker",
   "claim": "There are no free lunches in biology, and fighting biology usually loses.",
   "stance": "opinion",
   "conviction": 0.8,
   "subjects": [
    "testosterone",
    "melatonin"
   ],
   "timestamp": "4:43",
   "quote": "there are no free lunches in biology, and usually if you fight biology, you typically lose.",
   "episode_id": "the-diary-of-a-ceo-2026-06-26-most-replayed-moment-sleep-expert-on-the-truth-about-melaton",
   "published_at": "2026-06-26"
  },
  {
   "holder": "Kyle Gillett",
   "claim": "The key testosterone-related labs to check are either testosterone plus SHBG, or a free testosterone measurement.",
   "stance": "opinion",
   "conviction": 0.7,
   "subjects": [
    "testosterone",
    "SHBG"
   ],
   "timestamp": "1:19",
   "quote": "you want to get either testosterone and SHBG or a free testosterone.",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "holder": "Kyle Gillett",
   "claim": "A very restrictive carnivore or vegan diet is a bad idea for teens and men in their early 20s because it likely significantly decreases free androgens, though it might be a reasonable option in one's late 20s.",
   "stance": "opinion",
   "conviction": 0.75,
   "subjects": [
    "diet",
    "testosterone"
   ],
   "timestamp": "4:23",
   "quote": "In early 20s and certainly teens, it is a horrible idea because it is likely to significantly decrease your free androgens.",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "holder": "Kyle Gillett",
   "claim": "For someone not carrying excess body fat, being in a caloric deficit lowers testosterone because it reduces the building blocks for hormones, pushes the body toward a more catabolic state, and raises SHBG.",
   "stance": "assertion",
   "conviction": 0.75,
   "subjects": [
    "testosterone",
    "diet"
   ],
   "timestamp": "6:13",
   "quote": "If you look at an individual in a caloric deficit, several changes will happen. One is that they'll have less building blocks for hormones.",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "holder": "Kyle Gillett",
   "claim": "Regularly training vigorously for longer than an hour is not hormonally helpful, whereas three to four vigorous sessions a week is sustainable long-term.",
   "stance": "opinion",
   "conviction": 0.7,
   "subjects": [
    "exercise",
    "testosterone"
   ],
   "timestamp": "9:45",
   "quote": "The takeaway from that is basically do not, it is not hormonally helpful to train, especially regularly train vigorously for longer than an hour.",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "holder": "Kyle Gillett",
   "claim": "There is almost never a legitimate case for a man in his 20s with normal-range testosterone and estrogen to take exogenous testosterone.",
   "stance": "opinion",
   "conviction": 0.8,
   "subjects": [
    "testosterone replacement therapy (TRT)",
    "testosterone"
   ],
   "timestamp": "11:44",
   "quote": "Not very often if you're in your 20s and certainly probably almost hardly never.",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "holder": "Kyle Gillett",
   "claim": "Creatine slightly increases total testosterone and increases the conversion of testosterone to DHT, making it especially useful for men in their teens and 20s.",
   "stance": "opinion",
   "conviction": 0.65,
   "subjects": [
    "creatine",
    "testosterone",
    "DHT (dihydrotestosterone)"
   ],
   "timestamp": "12:43",
   "quote": "It does slightly increase total testosterone, and it also increases the conversion of testosterone to dihydrotestosterone.",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "holder": "Kyle Gillett",
   "claim": "Correcting a vitamin D deficiency will optimize testosterone.",
   "stance": "assertion",
   "conviction": 0.7,
   "subjects": [
    "vitamin D",
    "testosterone"
   ],
   "timestamp": "19:41",
   "quote": "if you have deficient vitamin D and you replace it, then you will optimize your testosterone.",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "holder": "Kyle Gillett",
   "claim": "Even in people with normal SHBG (where Tongkat Ali does nothing for SHBG itself), it will still increase their total and free testosterone.",
   "stance": "opinion",
   "conviction": 0.6,
   "subjects": [
    "Tongkat Ali",
    "testosterone",
    "SHBG"
   ],
   "timestamp": "23:29",
   "quote": "It'll increase their total and free testosterone.",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "holder": "Kyle Gillett",
   "claim": "A general normal starting dosing range for testosterone therapy is about 100-120 mg per week, divided over the course of the week rather than given as an infrequent large dose.",
   "stance": "opinion",
   "conviction": 0.75,
   "subjects": [
    "testosterone replacement therapy (TRT)",
    "testosterone"
   ],
   "timestamp": "27:59",
   "quote": "a general normal dosing range, especially for someone starting, is around 100 to 120 milligrams divided over the course of a week",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "holder": "Kyle Gillett",
   "claim": "A reasonable ceiling for alcohol intake is no more than three to four standard drinks (with a large wine glass counting as about five standard drinks) every two weeks.",
   "stance": "opinion",
   "conviction": 0.7,
   "subjects": [
    "alcohol",
    "testosterone"
   ],
   "timestamp": "35:25",
   "quote": "In general, I would not recommend more than three to four standard drinks.",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  }
 ],
 "predictions": [],
 "facts": [
  {
   "statement": "Vitamin D helps with testosterone production, bone mineralization, and stature.",
   "subjects": [
    "vitamin D",
    "testosterone"
   ],
   "timestamp": "3:20",
   "quote": "Vitamin D helps with testosterone production. It helps again with bone mineralization and stature.",
   "source": "Kyle Gillett",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "statement": "The normal reference range for testosterone cited in the discussion is 300 to 900 nanograms per deciliter.",
   "subjects": [
    "testosterone"
   ],
   "value": "300-900 ng/dL",
   "timestamp": "10:31",
   "quote": "if their blood levels are within the 300 to 900 nanograms per deciliter reference range?",
   "source": "Andrew Huberman",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  },
  {
   "statement": "Testosterone is normally released in a pulsatile manner, high in the morning and low in the evening, whereas testosterone therapy produces a steady state throughout the day.",
   "subjects": [
    "testosterone",
    "testosterone replacement therapy (TRT)"
   ],
   "timestamp": "28:56",
   "quote": "testosterone is normally released in a pulsatile manner. So it's high in the morning, low in the evening.",
   "source": "Kyle Gillett",
   "episode_id": "huberman-lab-2026-07-02-essentials-tools-for-hormone-optimization-in-males-dr-kyle-g",
   "published_at": "2026-07-02"
  }
 ],
 "first_seen": "2026-06-22",
 "last_seen": "2026-07-02"
}